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Cryptorchidism

Writer: Cedars SinaiCedars Sinai

Cryptorchidism, or undescended testicles, is a condition that affects 1 in 100 boys at birth. It occurs when one or both testicles fail to drop down into the scrotum, which can lead to various health risks if not treated.


What Causes Cryptorchidism?


The exact causes of cryptorchidism remain unclear, but several factors increase the chances of this condition occurring:


Genetic factors can significantly influence the likelihood of developing cryptorchidism. Studies show that boys with a family history are up to four times more likely to be affected.


Hormonal factors during pregnancy also play a role. For instance, low levels of testosterone, necessary for testicular descent, can lead to undescended testicles. Conditions like gestational diabetes increase this risk.


Environmental factors are being extensively researched. Studies suggest that exposure to chemicals, such as phthalates found in plastics, may disrupt hormone levels in pregnant women, potentially contributing to cryptorchidism.


Premature birth is another critical risk factor. Infants born before 37 weeks are three times more likely to have undescended testicles than those born full-term.


Recognizing the Symptoms of Cryptorchidism


Spotting the symptoms of cryptorchidism is often straightforward, especially in newborns:


The most obvious sign is the absence of one or both testicles in the scrotum. This can be observed during routine physical exams shortly after birth. If a parent notices that the testicles are positioned higher than normal—along the inguinal canal or in the abdomen—it may indicate a problem.


Generally, there is no pain associated with cryptorchidism in infancy. However, complications can arise as the child grows. These may include:


  • Testicular torsion: A painful condition that can occur if the spermatic cord twists, reducing blood flow to the testicle. This can happen in up to 25% of boys with undescended testicles.

  • Fertility issues: Research shows that undescended testicles can affect sperm production and quality. Males with a history of cryptorchidism are 4-5 times more likely to experience infertility later in life.


  • Increased cancer risk: Boys with untreated cryptorchidism have a 3-5 times greater risk of developing testicular cancer compared to their peers.


Diagnosis of Cryptorchidism


Diagnosing cryptorchidism typically begins with a physical examination. Pediatricians conduct thorough checks to locate the testicles during routine visits. In cases where the testicles are not easily found, imaging tests such as ultrasounds may be used to determine their location.


Understanding the position of the testicle is crucial for developing an effective treatment strategy.


Treatment Options for Cryptorchidism


Cryptorchidism treatment generally falls into two main categories: monitoring and surgical intervention.


Monitoring


For many infants, especially those younger than six months, doctors often recommend a period of observation. Around 80% of undescended testicles will naturally descend within the first year. Regular check-ups ensure that testicles are monitored for movement, reducing the need for intervention.


Surgical Intervention


If testicles do not descend on their own, surgery may be required. The procedure, known as orchidopexy, is typically performed between six months and one year. The steps of the surgery include:


  1. Anesthesia: The child receives general anesthesia for comfort.

  2. Incision: A surgeon makes an incision in either the groin or abdomen to locate the undescended testicle.


  3. Positioning: The testicle is then gently pulled down into the scrotum and securely fixed in place.


  4. Closure: The incision is closed with dissolvable stitches.


After surgery, monitoring for signs of complications, such as infection or swelling, is vital. Parents may need to limit physical activity during recovery to avoid pressure on the surgical area.


The Importance of Early Intervention


Timely diagnosis and treatment of cryptorchidism can prevent serious complications like infertility and testicular cancer. Early intervention also supports normal physical and psychological development. Research indicates that boys treated for this condition have more positive self-esteem and body image.


Parents should consult healthcare providers if they suspect their child has undescended testicles. Acting promptly can lead to much better health outcomes and peace of mind for families.


Final Thoughts


Cryptorchidism poses a significant challenge that warrants attention from both parents and healthcare professionals. By understanding its causes, symptoms, and treatment options, families can effectively manage this condition.


Early diagnosis and appropriate treatment can lead to healthier futures for boys affected by cryptorchidism, translating into a better quality of life and reduced health risks. Always consult a qualified healthcare provider with any concerns regarding your child's health to ensure effective management and care for cryptorchidism.

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