top of page

23. Hypothyroidism

Writer: Cedars SinaiCedars Sinai

Hypothyroidism is becoming more common, impacting millions worldwide. This condition occurs when the thyroid gland fails to produce enough hormones, which are critical for metabolism and energy management. Understanding its causes, symptoms, treatments, and lifestyle changes can empower those affected and help families and health professionals provide better support.


What is Hypothyroidism?


Hypothyroidism is an endocrine disorder where the thyroid gland, situated at the front of the neck, does not produce enough thyroid hormones, specifically thyroxine (T4) and triiodothyronine (T3). These hormones are essential for controlling metabolism, influencing how the body uses energy. When the thyroid is underactive, it can slow down various bodily functions, leading to a host of symptoms that significantly affect quality of life.


Causes of Hypothyroidism


Understanding the causes of hypothyroidism is crucial for both prevention and treatment. Some of the most common factors include:


Autoimmune Disease


The leading cause of hypothyroidism is Hashimoto's thyroiditis. In this autoimmune disorder, the immune system mistakenly attacks the thyroid, resulting in inflammation and damage. Studies show that more than 90% of hypothyroidism cases in the United States are due to Hashimoto's.


Iodine Deficiency


Iodine is critical for the production of T4 and T3 hormones. A lack of iodine can lead to decreased hormone production. According to the World Health Organization, about 2 billion people worldwide are estimated to be affected by iodine deficiency, even in regions where iodine is added to table salt.


Thyroid Surgery


Those who undergo thyroid surgery for nodules or cancer may experience hypothyroidism if a significant portion of their thyroid is removed.


Radiation Therapy


Radiation treatment for head and neck cancers can severely damage the thyroid gland, leading to reduced hormone production. Research indicates that up to 30% of patients receiving such treatments may develop hypothyroidism.


Medications


Certain drugs can interfere with thyroid function. For instance, lithium, often used for bipolar disorder, can lead to hypothyroidism in about 10-30% of patients.


Congenital Conditions


Some infants are born with congenital hypothyroidism due to an underdeveloped or absent thyroid gland. Early detection through newborn screening is essential, as untreated congenital hypothyroidism can result in severe developmental delays.


Pituitary Disorders


In rare instances, issues with the pituitary gland can lead to hypothyroidism. If the pituitary does not produce enough Thyroid Stimulating Hormone (TSH), it will fail to signal the thyroid to produce hormones.


Symptoms of Hypothyroidism


Hypothyroidism can exhibit a variety of symptoms. They may not be obvious initially and can vary in severity. Here are some common signs:


Fatigue


Many people with hypothyroidism report extreme fatigue that persists despite adequate rest. Research indicates that about 40% of individuals with hypothyroidism experience nearly constant fatigue.


Weight Gain


A slowed metabolism can cause unexplained weight gain. Clinical studies have shown that individuals may gain an average of 5 to 10 pounds within a few months after thyroid hormone levels fall.


Cold Intolerance


Heightened sensitivity to cold is common due to reduced metabolic activity. A survey found that over 50% of patients with hypothyroidism reported feeling cold more than their peers.


Dry Skin and Hair


This condition often leads to dry, rough skin and hair loss, with individuals frequently noticing increased brittleness and coarse texture.


Constipation


Many individuals find they experience constipation due to reduced gastrointestinal motility, affecting about 30% of those with low thyroid function.


Muscle Weakness


General muscle weakness, especially in the extremities, is another common symptom experienced by roughly 40% of patients.


Depression and Mood Swings


Hypothyroidism is linked to mood changes. Studies show that nearly 50% of patients report experiencing depression, anxiety, or mood fluctuations.


Memory Problems


Cognitive function can also decline. Research indicates that cognitive issues are present in about 60% of individuals with untreated hypothyroidism.


Hoarseness


A change in voice, particularly hoarseness, can occur due to swelling in the thyroid or surrounding tissues.


Menstrual Irregularities


Women may experience heavier or more irregular menstrual cycles due to hormonal imbalances, affecting roughly 30% of women with hypothyroidism.


Recognizing these symptoms is essential for proper diagnosis and treatment since they can overlap with other health conditions.



Treatment Options for Hypothyroidism


Managing hypothyroidism typically revolves around restoring hormone levels in the body. The most effective treatment includes:


Levothyroxine


Levothyroxine is a replacement thyroid hormone that helps to restore normal T4 levels. Taken once a day, it effectively normalizes thyroid hormone levels for about 80% of treated individuals.


Regular Monitoring


Regular blood tests to check TSH and T4 levels ensure that hormone levels are balanced. Patients typically have their levels monitored every 6 to 8 weeks after starting treatment, and then annually once stabilized.


Addressing Underlying Causes


If hypothyroidism stems from autoimmune conditions or medication side effects, it is crucial to address these underlying issues. Adjusting or changing medications can help.


Alternative Treatments


While some explore alternative therapies or supplements, it’s vital to consult healthcare providers before adding these to a treatment plan. Natural supplements like selenium may benefit some individuals, but results vary.


Lifestyle Changes for Managing Hypothyroidism


Alongside medication, several lifestyle changes can aid in managing hypothyroidism effectively:


Balanced Diet


Eating a diet rich in whole foods, fruits, vegetables, lean proteins, and healthy fats is beneficial. For instance, including omega-3 fatty acids from fatty fish can support heart health, particularly important for those with hypothyroidism.


Iodine Intake


For individuals with iodine deficiency, incorporating dietary sources like iodized salt, fish, dairy, and seaweed can improve hormone production. Aiming for an iodine intake of about 150 mcg per day is recommended for most adults.


Regular Exercise


Consistent physical activity combats fatigue, boosts metabolism, and enhances mental health. Studies show that regular exercise can improve mood and energy levels in individuals with hypothyroidism.


Stress Management


Adopting stress management practices such as mindfulness and meditation provides significant health benefits. Research demonstrates that reducing stress can improve overall well-being.


Adequate Sleep


Getting quality sleep is crucial for improving energy and optimizing metabolic health. Aiming for 7 to 9 hours of sleep per night can provide substantial benefits.


Regular Health Check-ups


Monitoring with healthcare providers is key. Regular follow-ups ensure prompt action if hormone levels shift, maintaining optimal health.


Wide angle view of a balanced meal showcasing fruits, vegetables, and lean proteins
A nutritious meal composed of colorful vegetables, fruits, and lean proteins.

Final Thoughts


Hypothyroidism is manageable with the right understanding and approaches. Recognizing the causes, symptoms, and treatment options is vital for both patients and healthcare providers.


By maintaining a balanced diet, exercising regularly, and staying informed, individuals with hypothyroidism can live fulfilling lives. Engaging with healthcare professionals for ongoing support ensures any changes are quickly addressed, promoting better overall health and well-being.


High angle view of healthy lifestyle choices including exercise equipment and nutritious foods
A motivational setting displaying fitness gear alongside healthy food options.

Recent Posts

See All

High Cholesterol

Cholesterol is a waxy substance found in the blood. The body needs cholesterol to build healthy cells. But high levels of cholesterol can...

Hashimoto's disease

Hashimoto's disease is an autoimmune disorder affecting the thyroid gland. The thyroid is a butterfly-shaped gland located at the base of...

Graves' disease

Graves' disease is an immune system condition that affects the thyroid gland. It causes the body to make too much thyroid hormone. That...

Comments


Commenting has been turned off.
bottom of page